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University of Nottingham
Managed Chemical Compound Collection
    Microscopes

    MCCC Facility Equipment

    TTP comPOUND Equipment

    TTPcomPOUND

    • High-density sample storage unit: up to 100k tubes
    • Controlled internal conditions: temperature control, dry and inert
    • Fast cherry picking of tubes that are needed: reducing potential damage to library stocks
    • Output to 96-well rack
    • Ca. 15 min to store / retrieve a full rack
    • Additional modules can be integrated as the collection grows

    TTPcomPILER

    • Tube-to-plate processing system
    • Tubes retrieved from comPOUND and assembled in racks
    • Racks pass through several stations:
    • Heating Tunnel
    • Centrifuge
    • De-capper
    • Liquid dispenser (Tecan)
    • Re-capper
    • Finally rack delivered to Arrayer for re-storage in comPOUND.
    • Tubes filled with Ar during processing to maintain sample microenvironment
    TTP comPILER Equipment

    Tecan Freedom Evo

    • Liquid handling unit
      • 96 channel liquid dispensing head
      • Disposable nested tips
      • Robotic arm
      • Carousel plate storage
      • 200 plate capacity
      • HeatSealer
    • Fully integrated with TTP equipment
      • Communication via bespoke software Duccio
    Tecan Freedom Evo

    Shimadzu LC2020

    • Ultra high-speed mass spectrometer coupled with ultra high-speed liquid chromatography
    • Features
      • Autosampler configured for vials and plates
      • Dual ionisation source
    Shimadzu Equipment

    Data management

    • Oracle Database and user interface
    • ActivityBase (IDBS)
    Data Management ui
    Person Storing Compound